Stein Gives Bioinformatics Ten Years to Live. Lincoln Stein reflects on the role of bioinformatics in his keynote address at the O'Reilly Bioinformatics Technology Conference. [O'Reilly Network Articles]
Here is a link to Lincoln's discussion. It was quite provocative. [A Man with a Ph.D. – Richard Gayle's Weblog]
10 years is a long time, a very long time. i'd say 7 tops, that would be around 4 revolutions of computational power and perhaps 2 revolutions in theoretical applications.