Here is my current definition of cultural informatics
Cultural Informatics is the application and understandings of information technology in the broadest senses of cultures and cultural institutions.
Here is an expansion and clarification:
To that end, it deals with understandings of culturally centered information, cultural heritage, cultural communities, the transmission of information through cultures and relations between culture and information technology. While there are productive, design and creative elements to cultural informatics, that design has to be understood as constructed within a rich cultural milieu, and situated as such as part of a process to generate understanding within and across cultures. Cultural informatics must continually be reflexive and critical of the systems we create and participate in order to generate new possibilities that will work across cultural domains. It is not enough to build the tool, we build the tool in a culture, and we build cultural and political assumptions into that tool which have clear implications for the positioning of cultures, peoples, and technologies.